What I'd normally do when I am setting up a quiz, not a regular occurrence but I have done it once or twice, is get a group of three or four friends around a table and a big pile of encyclopaedia, general interest books, basically anything factual and then set out a few headings to have questions for. They don't have be rounds but it makes it easier to set out questions if you use headings such as Sport, TV, History, Geography, Books, Music, etc. You can mix and match the rounds then afterwards and it helps them stay more balanced if you have already set out a few topics. If you are likely to know a lot of people there a few questions that have a more personal interest reference (say you know a good 30% of the teams will have someone who is involved in the same club as you, then set questions on the activity you do) are good and always ask local questions. If you are organising for a charity or if you are raising sponsorship to do an event, throw in a few questions on that topic too. The other thing is to have a round that people can be playing with as they are chatting between rounds, it takes a few minutes to gather in all the papers and then marking them is a pain (which is why it is also a good idea to have the friends that set the quiz mark it and why it is a good idea to have a set of friends set the questions!!) Generally I will go for a puzzle round rather than a pictures round, the reason being that generally photocopies in black and white are quite poor for pictures and it is more expensive to get the colour copies. Puzzles tend to be printed in black and white anyway so photocopy better. If you do puzzles, the cryptic rebus ones in the Herald AM are ideal, not too much writing in (Sudoku is a bad idea for example) but something a little challenging.
Long-winded...
Short version
1) Don't be afraid to do it yourself, get a few mates together and knock a few rounds up, then shamelessly use them to mark the papers because they won't be able to partake of the quiz
2) Set a few headings/topics to give you some ideas and then once you have enough questions (60-80 max) set up your rounds
3) Do local and personal interest.
4) Do a round that you hand out about round 2 and don't gather until round 7, make it pictorial but generally (unless you want to spend the money on it) avoid pictures of people.
5) Another tip, have three tie-break questions you probably won't need them but just in case.
6) And have a couple of spot prize questions on the rounds, either a sort of best answer wins type of question, no right and wrong to it or really, really hard! Don't mark them as part of a round though. And of course a spot prize for best team name.
7) For marking it is generally easier if the number of points matches the number of questions, so avoid the multiple answer questions because they are just more difficult to mark fairly.