Have you specified what make/model/ of boiler you want?
Have plumbers specified what boiler they will use, make/model/output?
Do you want your home to be piped with no fittings in unaccessible places I.E under floors etc?
This would be achieved by running separate lines to eveything(sinks,radiators etc) and bringing them back to a centre manifold. 1 or two manifolds for plumbing and a manifold for each heating zone.
This is more costly (more labour/material used) than having a main line(every zone having its own main line) with tee's off it. but you are nearly 100% sure of no leaks under floors for the properties life time.
You should ask them to specify what electrical parts they plan to use e.g circulation pumps and motorised/zone valves on heating. Prices vary greatly depending on quality.
How many pumps will heating system have?
What size cylinder?
Will cylinder have stat?
What make are TRV's?
Will bathroom radiators/towel warmers be piped into primary circuit? I.E When hot water only is on (summer time), bathroom heat source is on?
How many runs in insulated pipe from boiler to house?
You want the incased pre-insulated ducted pipe. It is expensive but worth every penny in the long run.