I'd say 30-35% of you net income is about right. BUT remember if you are doing this with a 30-40 year loan you are paying 100's of thousands more in interest to the bank than you would if you could do it over 20-25 years.Keep the lenght of the loan as short as possible.
HAve you looked at the senario of what would happen if you had to live of one income? could you? You have good savings to use in a critical situation at the momment but will you be using this saftely net when buying the house? Some say you should have 6 months salary at least stuck away just in case but this is not practical for most.
Rememeber lifestyle and quality of life could be important factors, depend on your priorities in life. We aren't around for that long so is a house important to you or do you want to eat out, have 2-3 holidays a year, have children with out having to worry about money etc.
There is a balance some where, depending on what you want out of life. I am lucky enough to earn a good 6 figure salary but have choosen to live in a normal 3 bed end of terrace as I didn't want a mortage over more than 20 years.
Friends have more debt, bigger houses and more money worries. As a family with 2 kids we have a great great quality of life which I would not change!
It personal preference but worth thinking about.