If you have no plans to sell in the near future, then I'd do it.
Assuming it is just a corner of the room that is blocked off with two stud partitions. This is most likely as you said, (no supporting walls), easily established by tapping on the walls.
All the ensuite is is a water inlets for the sink (2) toilet (1) and shower (1 or 2), and a waste outlet for the toilet, sink and shower. It isn't a major deal to cap these off in such a way that they can be re-used or re-opened down the line if your situation changes or you sell. In the meantime you have a more functional bedroom. We did the same in our house with the "under the stairs" toilet. Capped of the sink and toilet and put a washing machine in there instead. When we sold the house we showed the new buyers that they could convert back to a toilet room if they wished.