Brendan Burgess
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Admission of mistake in Oxford vaccine dose raises doubts over reliability
Odds of regulators quickly authorising emergency use of inoculation are declining
www.irishtimes.com
Officials in the United States have noted that the results were not clear. It was the head of the flagship federal vaccine initiative — not the company — who first disclosed that the vaccine’s most promising results did not reflect data from older people.
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The biggest questions were, why was there such a large variation in the effectiveness of the vaccine at different doses, and why did a smaller dose appear to produce much better results? AstraZeneca and Oxford researchers said they did not know.