I have been considering this recently, as I would desperately like to get out of Dublin but the job situation seems to be a lot worse elsewhere in the country.
Basically as far as I know and as much as I've read, social welfare offices can't use you moving somewhere with less job prospects etc as a reason to delay or refuse entitlement payments (the way I see it is, you may move from Dublin to Cork lets say because there is a lower cost of living i.e. rent). They have to treat you like any other person coming in to sign on for what you are entitled to. I think there is a significant wait period when you voluntarily leave a job, possibly 9 weeks but I'm open to correction.