It is serious. A proper job would involve gutting at least the room (or whole house) removing the floors, stripping all the plaster off the walls, treating all with very strong chemicals (you could not live in the house while this is being done), fixing what ever caused problem in the first place (new DPC, drains etc). Then putting in a new floor, replastering, skirting, electrics, central heading etc. We had all that professionaly done to a house and after 20 years it was back. The reality is that most big old houses have some and most people just live with it.