A colleague went on 2-week holiday last year but between rule changes while he was away and him unfortunately getting Covid he ended up stuck abroad for almost 6 weeks. Important to think about this if you have work commitments or children involved.As @NoRegretsCoyote said, Covid is everywhere. I would consider how I would handle Covid in Spain versus at home? Will you have access to separate rooms / out door space when in Spain? I think it would be very difficult to be isolating in a hotel room versus at home, but perhaps you've booked something larger. At home, I know how to get food delivered, friends to drop things to door, etc... Depending on language skills, where you're going this might be harder.