It will depend on the system you have and the conditions of the installation particular to your exact conditions.
For example, if your system is an open vented system, many are installed with the f & e tank located over the cwst. This is illegal however very common. It could also have it's overflow pipe piped into the cwst, also very common but incorrect. If your ball valve fails, it will overflow mixed anti-freeze into your domestic water.
If you have a sealed system, then I suppose the risks are the same that of a solar system, at the coil in the domestic hw cylinder. If this fails, anti-freeze will enter the domestic water system.